When Jesus was about to leave the disciples 3 things happened.
1. He blessed them
2. Instructed them to remain in Jerusalem.
3. They were to wait for the Holy Spirit to be upon them.
It is dangerous to start a ministry without being led by the Spirit. 1 Corinthians 2:10-11 But God has revealed them to us through His Spirit. For the Spirit searches all things, yes, the deep things of God. For what man knows the things of a man except the spirit of the man which is in him? Even so no one knows the things of God except the Spirit of God.